1jf7: Difference between revisions
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[[Image:1jf7.png|left|200px]] | [[Image:1jf7.png|left|200px]] | ||
{{STRUCTURE_1jf7| PDB=1jf7 | SCENE= }} | {{STRUCTURE_1jf7| PDB=1jf7 | SCENE= }} | ||
===HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836=== | ===HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836=== | ||
{{ABSTRACT_PUBMED_11806712}} | {{ABSTRACT_PUBMED_11806712}} | ||
==About this Structure== | ==About this Structure== | ||
[[1jf7]] is a 2 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JF7 OCA]. | |||
==See Also== | |||
*[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | |||
*[[Tyrosine phosphatase|Tyrosine phosphatase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:011806712</ref><ref group="xtra">PMID:015258570</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
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[[Category: Sullivan, T J.O.]] | [[Category: Sullivan, T J.O.]] | ||
[[Category: Complex]] | [[Category: Complex]] | ||
[[Category: Hydrolase]] | |||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Tyrosine phosphatase]] | [[Category: Tyrosine phosphatase]] | ||
Revision as of 08:06, 26 July 2012
HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836
Template:ABSTRACT PUBMED 11806712
About this Structure
1jf7 is a 2 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Larsen SD, Barf T, Liljebris C, May PD, Ogg D, O'Sullivan TJ, Palazuk BJ, Schostarez HJ, Stevens FC, Bleasdale JE. Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B. J Med Chem. 2002 Jan 31;45(3):598-622. PMID:11806712
- Wiesmann C, Barr KJ, Kung J, Zhu J, Erlanson DA, Shen W, Fahr BJ, Zhong M, Taylor L, Randal M, McDowell RS, Hansen SK. Allosteric inhibition of protein tyrosine phosphatase 1B. Nat Struct Mol Biol. 2004 Aug;11(8):730-7. Epub 2004 Jul 18. PMID:15258570 doi:10.1038/nsmb803