3dv5: Difference between revisions

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{{Seed}}
[[Image:3dv5.png|left|200px]]
[[Image:3dv5.png|left|200px]]


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{{STRUCTURE_3dv5|  PDB=3dv5  |  SCENE=  }}  
{{STRUCTURE_3dv5|  PDB=3dv5  |  SCENE=  }}  


===Crystal structure of human beta-secretase in complex with NVP-BAV544===
===Crystal structure of human beta-secretase in complex with NVP-BAV544===


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{{ABSTRACT_PUBMED_19195887}}
{{ABSTRACT_PUBMED_19195887}}


==About this Structure==
==About this Structure==
3DV5 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DV5 OCA].  
[[3dv5]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DV5 OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19195887</ref><references group="xtra"/>
<ref group="xtra">PMID:019195887</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Rondeau, J M.]]
[[Category: Rondeau, J M.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 14:55:21 2009''

Revision as of 08:32, 26 July 2012

File:3dv5.png

Template:STRUCTURE 3dv5

Crystal structure of human beta-secretase in complex with NVP-BAV544

Template:ABSTRACT PUBMED 19195887

About this Structure

3dv5 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U. Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. Epub 2009 Jan 22. PMID:19195887 doi:10.1016/j.bmcl.2009.01.055

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