3lu9: Difference between revisions

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[[Image:3lu9.png|left|200px]]
[[Image:3lu9.png|left|200px]]


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{{STRUCTURE_3lu9|  PDB=3lu9  |  SCENE=  }}  
{{STRUCTURE_3lu9|  PDB=3lu9  |  SCENE=  }}  


===Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1===
===Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1===


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{{ABSTRACT_PUBMED_20236938}}
{{ABSTRACT_PUBMED_20236938}}


==About this Structure==
==About this Structure==
[[3lu9]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LU9 OCA].  
[[3lu9]] is a 6 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LU9 OCA].  
 
==See Also==
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:20236938</ref><ref group="xtra">PMID:15152000</ref><references group="xtra"/>
<ref group="xtra">PMID:020236938</ref><ref group="xtra">PMID:015152000</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cell membrane]]
[[Category: Cell membrane]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
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[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Pharmaceutical]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Receptor]]
[[Category: Receptor]]

Revision as of 08:36, 26 July 2012

File:3lu9.png

Template:STRUCTURE 3lu9

Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1

Template:ABSTRACT PUBMED 20236938

About this Structure

3lu9 is a 6 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Gandhi PS, Chen Z, Di Cera E. Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1. J Biol Chem. 2010 May 14;285(20):15393-8. Epub 2010 Mar 17. PMID:20236938 doi:10.1074/jbc.M110.115337
  2. Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200

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