3f0b: Difference between revisions

Revision as of 09:06, 26 July 2012

3f0b is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.

Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045

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 [[Image:3f0b.png|left|200px]]
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 ===Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine===
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 ==See Also==
-*[[Dihydrofolate reductase]]
+*[[Dihydrofolate reductase|Dihydrofolate reductase]]
 ==Reference==
-<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
+<ref group="xtra">PMID:019249312</ref><references group="xtra"/>
 [[Category: Dihydrofolate reductase]]
 [[Category: Staphylococcus aureus rf122]]