3l2v: Difference between revisions

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[[Image:3l2v.png|left|200px]]
[[Image:3l2v.png|left|200px]]


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{{STRUCTURE_3l2v|  PDB=3l2v  |  SCENE=  }}  
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===Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518 (Raltegravir)===
===Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518 (Raltegravir)===


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{{ABSTRACT_PUBMED_20118915}}
{{ABSTRACT_PUBMED_20118915}}


==About this Structure==
==About this Structure==
[[3l2v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_spumaretrovirus Human spumaretrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L2V OCA].  
[[3l2v]] is a 4 chain structure of [[Retroviral Integrase]] with sequence from [http://en.wikipedia.org/wiki/Human_spumaretrovirus Human spumaretrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L2V OCA].  


==See Also==
==See Also==
*[[Raltegravir]]
*[[Raltegravir|Raltegravir]]
*[[Retroviral Integrase|Retroviral Integrase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20118915</ref><references group="xtra"/>
<ref group="xtra">PMID:020118915</ref><references group="xtra"/>
[[Category: Human spumaretrovirus]]
[[Category: Human spumaretrovirus]]
[[Category: Cherepanov, P.]]
[[Category: Cherepanov, P.]]
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[[Category: Viral protein]]
[[Category: Viral protein]]
[[Category: Virion]]
[[Category: Virion]]
[[Category: Zinc]]
[[Category: Zinc binding]]
[[Category: Zinc binding]]

Revision as of 09:07, 26 July 2012

File:3l2v.png

Template:STRUCTURE 3l2v

Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518 (Raltegravir)

Template:ABSTRACT PUBMED 20118915

About this Structure

3l2v is a 4 chain structure of Retroviral Integrase with sequence from Human spumaretrovirus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hare S, Gupta SS, Valkov E, Engelman A, Cherepanov P. Retroviral intasome assembly and inhibition of DNA strand transfer. Nature. 2010 Mar 11;464(7286):232-6. Epub 2010 Jan 31. PMID:20118915 doi:10.1038/nature08784

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