3h0e: Difference between revisions
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[[Image:3h0e.png|left|200px]] | |||
[[Image:3h0e. | |||
{{STRUCTURE_3h0e| PDB=3h0e | SCENE= }} | {{STRUCTURE_3h0e| PDB=3h0e | SCENE= }} | ||
===3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as Potent Non-Peptidic Inhibitors of Caspase-3=== | ===3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as Potent Non-Peptidic Inhibitors of Caspase-3=== | ||
{{ABSTRACT_PUBMED_19836248}} | {{ABSTRACT_PUBMED_19836248}} | ||
==About this Structure== | ==About this Structure== | ||
[[3h0e]] is a 2 chain structure of [[Caspase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0E OCA]. | |||
==See Also== | |||
*[[Caspase|Caspase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019836248</ref><references group="xtra"/> | ||
[[Category: Caspase-3]] | [[Category: Caspase-3]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Caspase-3]] | [[Category: Caspase-3]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
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[[Category: Thiol protease]] | [[Category: Thiol protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 09:50, 26 July 2012
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as Potent Non-Peptidic Inhibitors of Caspase-3
Template:ABSTRACT PUBMED 19836248
About this Structure
3h0e is a 2 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Havran LM, Chong DC, Childers WE, Dollings PJ, Dietrich A, Harrison BL, Marathias V, Tawa G, Aulabaugh A, Cowling R, Kapoor B, Xu W, Mosyak L, Moy F, Hum WT, Wood A, Robichaud AJ. 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3. Bioorg Med Chem. 2009 Nov 15;17(22):7755-68. Epub 2009 Sep 24. PMID:19836248 doi:10.1016/j.bmc.2009.09.036