2gqv: Difference between revisions

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[[Image:2gqv.png|left|200px]]
[[Image:2gqv.png|left|200px]]


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{{STRUCTURE_2gqv|  PDB=2gqv  |  SCENE=  }}  
{{STRUCTURE_2gqv|  PDB=2gqv  |  SCENE=  }}  


===High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site===
===High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site===


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{{ABSTRACT_PUBMED_16790925}}
{{ABSTRACT_PUBMED_16790925}}


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==See Also==
==See Also==
*[[Dihydrofolate reductase]]
*[[Dihydrofolate reductase|Dihydrofolate reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16790925</ref><ref group="xtra">PMID:7583655</ref><ref group="xtra">PMID:3530319</ref><references group="xtra"/>
<ref group="xtra">PMID:016790925</ref><ref group="xtra">PMID:007583655</ref><ref group="xtra">PMID:003530319</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]

Revision as of 09:52, 26 July 2012

File:2gqv.png

Template:STRUCTURE 2gqv

High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site

Template:ABSTRACT PUBMED 16790925

About this Structure

2gqv is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Narayana N. High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site. Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):695-706. Epub 2006, Jun 20. PMID:16790925 doi:S0907444906014764
  2. Narayana N, Matthews DA, Howell EE, Nguyen-huu X. A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. Nat Struct Biol. 1995 Nov;2(11):1018-25. PMID:7583655
  3. Matthews DA, Smith SL, Baccanari DP, Burchall JJ, Oatley SJ, Kraut J. Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67. Biochemistry. 1986 Jul 29;25(15):4194-204. PMID:3530319

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