3iw4: Difference between revisions
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[[Image:3iw4.png|left|200px]] | [[Image:3iw4.png|left|200px]] | ||
{{STRUCTURE_3iw4| PDB=3iw4 | SCENE= }} | {{STRUCTURE_3iw4| PDB=3iw4 | SCENE= }} | ||
===Crystal structure of PKC alpha in complex with NVP-AEB071=== | ===Crystal structure of PKC alpha in complex with NVP-AEB071=== | ||
{{ABSTRACT_PUBMED_19827831}} | {{ABSTRACT_PUBMED_19827831}} | ||
==About this Structure== | ==About this Structure== | ||
[[3iw4]] is a 3 chain structure of [[Protein kinase C]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA]. | |||
==See Also== | |||
*[[Protein kinase C|Protein kinase C]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019827831</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein kinase C]] | [[Category: Protein kinase C]] | ||
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[[Category: Strauss, A.]] | [[Category: Strauss, A.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
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[[Category: Phorbol-ester binding]] | [[Category: Phorbol-ester binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 10:01, 26 July 2012
Crystal structure of PKC alpha in complex with NVP-AEB071
Template:ABSTRACT PUBMED 19827831
About this Structure
3iw4 is a 3 chain structure of Protein kinase C with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wagner J, von Matt P, Sedrani R, Albert R, Cooke N, Ehrhardt C, Geiser M, Rummel G, Stark W, Strauss A, Cowan-Jacob SW, Beerli C, Weckbecker G, Evenou JP, Zenke G, Cottens S. Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5 -dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes. J Med Chem. 2009 Oct 22;52(20):6193-6. PMID:19827831 doi:10.1021/jm901108b
