3ql3: Difference between revisions

Revision as of 10:17, 26 July 2012

3ql3 is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 1997 Jan 21;36(3):586-603. PMID:9012674 doi:https://dx.doi.org/10.1021/bi962337c
Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE. A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science. 2011 Apr 8;332(6026):234-8. PMID:21474759 doi:10.1126/science.1198542

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 [[Image:3ql3.png|left|200px]]
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 ===Re-refined coordinates for PDB entry 1RX2===
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