1kw0: Difference between revisions

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{{Seed}}
[[Image:1kw0.png|left|200px]]
[[Image:1kw0.png|left|200px]]


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{{STRUCTURE_1kw0|  PDB=1kw0  |  SCENE=  }}  
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===Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine===
===Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine===


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{{ABSTRACT_PUBMED_12126628}}
{{ABSTRACT_PUBMED_12126628}}


==Disease==
==About this Structure==
Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]]
[[1kw0]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KW0 OCA].


==About this Structure==
==See Also==
1KW0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KW0 OCA].
*[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]]


==Reference==
==Reference==
<ref group="xtra">PMID:12126628</ref><references group="xtra"/>
<ref group="xtra">PMID:012126628</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylalanine 4-monooxygenase]]
[[Category: Phenylalanine 4-monooxygenase]]
Line 34: Line 22:
[[Category: Basket-arrangement 13 alpha-helices and 6 beta-strand]]
[[Category: Basket-arrangement 13 alpha-helices and 6 beta-strand]]
[[Category: Ferrous iron]]
[[Category: Ferrous iron]]
 
[[Category: Oxidoreductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:53:10 2009''

Revision as of 10:50, 26 July 2012

File:1kw0.png

Template:STRUCTURE 1kw0

Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine

Template:ABSTRACT PUBMED 12126628

About this Structure

1kw0 is a 1 chain structure of Phenylalanine hydroxylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628

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