2ven: Difference between revisions
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[[Image:2ven.png|left|200px]] | [[Image:2ven.png|left|200px]] | ||
{{STRUCTURE_2ven| PDB=2ven | SCENE= }} | {{STRUCTURE_2ven| PDB=2ven | SCENE= }} | ||
===STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES=== | ===STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES=== | ||
{{ABSTRACT_PUBMED_18239072}} | {{ABSTRACT_PUBMED_18239072}} | ||
==About this Structure== | ==About this Structure== | ||
[[2ven]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEN OCA]. | [[2ven]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEN OCA]. | ||
==See Also== | |||
*[[TIM test|TIM test]] | |||
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]] | |||
==Reference== | ==Reference== | ||
Revision as of 11:08, 26 July 2012
STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES
Template:ABSTRACT PUBMED 18239072
About this Structure
2ven is a 2 chain structure of TIM test and Triose Phosphate Isomerase with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.
See Also
Reference
- Alahuhta M, Salin M, Casteleijn MG, Kemmer C, El-Sayed I, Augustyns K, Neubauer P, Wierenga RK. Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties. Protein Eng Des Sel. 2008 Apr;21(4):257-66. Epub 2008 Jan 31. PMID:18239072 doi:https://dx.doi.org/10.1093/protein/gzn002