3fz1: Difference between revisions

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{{Seed}}
[[Image:3fz1.png|left|200px]]
[[Image:3fz1.png|left|200px]]


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{{STRUCTURE_3fz1|  PDB=3fz1  |  SCENE=  }}  
{{STRUCTURE_3fz1|  PDB=3fz1  |  SCENE=  }}  


===Crystal structure of a benzthiophene inhibitor bound to human Cyclin-dependent Kinase-2 (CDK-2)===
===Crystal structure of a benzthiophene inhibitor bound to human Cyclin-dependent Kinase-2 (CDK-2)===


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{{ABSTRACT_PUBMED_19616942}}
{{ABSTRACT_PUBMED_19616942}}


==About this Structure==
==About this Structure==
3FZ1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FZ1 OCA].  
[[3fz1]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FZ1 OCA].  
 
==See Also==
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]


==Reference==
==Reference==
<ref group="xtra">PMID:19616942</ref><references group="xtra"/>
<ref group="xtra">PMID:019616942</ref><references group="xtra"/>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Ser/thr kinase]]
[[Category: Ser/thr kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 20:15:54 2009''

Revision as of 11:12, 26 July 2012

File:3fz1.png

Template:STRUCTURE 3fz1

Crystal structure of a benzthiophene inhibitor bound to human Cyclin-dependent Kinase-2 (CDK-2)

Template:ABSTRACT PUBMED 19616942

About this Structure

3fz1 is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Anderson DR, Meyers MJ, Kurumbail RG, Caspers N, Poda GI, Long SA, Pierce BS, Mahoney MW, Mourey RJ, Parikh MD. Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4882-4. Epub 2009 Feb 8. PMID:19616942 doi:10.1016/j.bmcl.2009.02.017

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