3kl6: Difference between revisions

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{{Seed}}
[[Image:3kl6.png|left|200px]]
[[Image:3kl6.png|left|200px]]


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{{STRUCTURE_3kl6|  PDB=3kl6  |  SCENE=  }}  
{{STRUCTURE_3kl6|  PDB=3kl6  |  SCENE=  }}  


===Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor===
===Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor===


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{{ABSTRACT_PUBMED_20355714}}
{{ABSTRACT_PUBMED_20355714}}


==Disease==
==About this Structure==
Known disease associated with this structure: Factor X deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227600 227600]]
[[3kl6]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KL6 OCA].


==About this Structure==
==See Also==
3KL6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KL6 OCA].
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
<ref group="xtra">PMID:20355714</ref><references group="xtra"/>
<ref group="xtra">PMID:020355714</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aertgeerts, K.]]
[[Category: Aertgeerts, K.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Coagulation factor xa]]
[[Category: Coagulation factor xa]]
Line 40: Line 27:
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Hydroxylation]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:06:26 2010''
Retrieved from "https://proteopedia.org/3kl6"