1yrs: Difference between revisions

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{{Seed}}
[[Image:1yrs.png|left|200px]]
[[Image:1yrs.png|left|200px]]


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===Crystal structure of KSP in complex with inhibitor 1===
===Crystal structure of KSP in complex with inhibitor 1===


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{{ABSTRACT_PUBMED_15808464}}
{{ABSTRACT_PUBMED_15808464}}


==About this Structure==
==About this Structure==
1YRS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YRS OCA].  
[[1yrs]] is a 2 chain structure of [[Kinesin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YRS OCA].  
 
==See Also==
*[[Kinesin|Kinesin]]
*[[Kinesin-5|Kinesin-5]]


==Reference==
==Reference==
<ref group="xtra">PMID:15808464</ref><references group="xtra"/>
<ref group="xtra">PMID:015808464</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Breslin, M J.]]
[[Category: Breslin, M J.]]
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[[Category: Yan, Y.]]
[[Category: Yan, Y.]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 23 13:25:29 2010''

Revision as of 12:08, 26 July 2012

File:1yrs.png


Drag the structure with the mouse to rotate
1yrs, resolution 2.50Å (default scene)
Ligands: ADP, L47, MG
Gene: KIF11, EG5, KNSL1 (Homo sapiens)
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Crystal structure of KSP in complex with inhibitor 1

Template:ABSTRACT PUBMED 15808464

About this Structure

1yrs is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cox CD, Breslin MJ, Mariano BJ, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Huber HE, Kohl NE, Torrent M, Yan Y, Kuo LC, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2041-5. PMID:15808464 doi:10.1016/j.bmcl.2005.02.055

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