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Revision as of 12:43, 26 July 2012

File:3mk8.png

Template:STRUCTURE 3mk8

The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer

Template:ABSTRACT PUBMED 20562877

About this Structure

3mk8 is a 2 chain structure of Bcl-2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Stewart ML, Fire E, Keating AE, Walensky LD. The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer. Nat Chem Biol. 2010 Aug;6(8):595-601. Epub 2010 Jun 20. PMID:20562877 doi:10.1038/nchembio.391

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