3ooz: Difference between revisions

Revision as of 12:53, 26 July 2012

3ooz is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Malamas MS, Robichaud A, Erdei J, Quagliato D, Solvibile W, Zhou P, Morris K, Turner J, Wagner E, Fan K, Olland A, Jacobsen S, Reinhart P, Riddell D, Pangalos M. Design and synthesis of aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors with enhanced brain permeability. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6597-605. Epub 2010 Sep 15. PMID:20880704 doi:10.1016/j.bmcl.2010.09.029

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-[[Image:3ooz.jpg|left|200px]]
+[[Image:3ooz.png|left|200px]]
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 ===Bace1 in complex with the aminohydantoin Compound 102===
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 ==About this Structure==
-[[3ooz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOZ OCA].
+[[3ooz]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOZ OCA].
+==See Also==
+*[[Beta secretase|Beta secretase]]
 ==Reference==