3e4z: Difference between revisions

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{{Seed}}
[[Image:3e4z.png|left|200px]]
[[Image:3e4z.png|left|200px]]


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{{STRUCTURE_3e4z|  PDB=3e4z  |  SCENE=  }}  
{{STRUCTURE_3e4z|  PDB=3e4z  |  SCENE=  }}  


===Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II===
===Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II===


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{{ABSTRACT_PUBMED_19896952}}
{{ABSTRACT_PUBMED_19896952}}


==Disease==
==About this Structure==
Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147470 147470]]
[[3e4z]] is a 4 chain structure of [[Insulin-Degrading Enzyme]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E4Z OCA].


==About this Structure==
==See Also==
3E4Z is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E4Z OCA].
*[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]]


==Reference==
==Reference==
<ref group="xtra">PMID:19896952</ref><references group="xtra"/>
<ref group="xtra">PMID:019896952</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Insulysin]]
[[Category: Insulysin]]
Line 32: Line 20:
[[Category: Manolopoulou, M.]]
[[Category: Manolopoulou, M.]]
[[Category: Tang, W J.]]
[[Category: Tang, W J.]]
[[Category: Alternative splicing]]
[[Category: Complex]]
[[Category: Complex]]
[[Category: Degrading]]
[[Category: Degrading]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Growth factor]]
[[Category: Growth factor]]
[[Category: Hydrolase/hormone complex]]
[[Category: Hydrolase-hormone complex]]
[[Category: Ide]]
[[Category: Ide]]
[[Category: Igf-ii]]
[[Category: Igf-ii]]
[[Category: Mitogen]]
[[Category: Mitogen]]
[[Category: Polymorphism]]
[[Category: Secreted]]
[[Category: Secreted]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 15:53:16 2010''

Revision as of 14:28, 26 July 2012

File:3e4z.png

Template:STRUCTURE 3e4z

Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II

Template:ABSTRACT PUBMED 19896952

About this Structure

3e4z is a 4 chain structure of Insulin-Degrading Enzyme with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072

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