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[[Image:2wgs.png|left|200px]]
[[Image:2wgs.png|left|200px]]


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{{STRUCTURE_2wgs|  PDB=2wgs  |  SCENE=  }}  
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===CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH A PURINE ANALOGUE INHIBITOR.===
===CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH A PURINE ANALOGUE INHIBITOR.===


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{{ABSTRACT_PUBMED_19695264}}


==About this Structure==
==About this Structure==
[[2wgs]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGS OCA].  
[[2wgs]] is a 12 chain structure of [[Glutamine Synthase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGS OCA].  
 
==See Also==
*[[Glutamine Synthase|Glutamine Synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19695264</ref><ref group="xtra">PMID:16027359</ref><references group="xtra"/>
<ref group="xtra">PMID:019695264</ref><ref group="xtra">PMID:016027359</ref><references group="xtra"/>
[[Category: Glutamate--ammonia ligase]]
[[Category: Glutamate--ammonia ligase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Mowbray, S L.]]
[[Category: Mowbray, S L.]]
[[Category: Nilsson, M T.]]
[[Category: Nilsson, M T.]]
[[Category: Cytoplasm]]
[[Category: Glna1]]
[[Category: Glna1]]
[[Category: Ligase]]
[[Category: Ligase]]

Revision as of 14:31, 26 July 2012

File:2wgs.png

Template:STRUCTURE 2wgs

CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH A PURINE ANALOGUE INHIBITOR.

Template:ABSTRACT PUBMED 19695264

About this Structure

2wgs is a 12 chain structure of Glutamine Synthase with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Nilsson MT, Krajewski WW, Yellagunda S, Prabhumurthy S, Chamarahally GN, Siddamadappa C, Srinivasa BR, Yahiaoui S, Larhed M, Karlen A, Jones TA, Mowbray SL. Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors. J Mol Biol. 2009 Oct 23;393(2):504-13. Epub 2009 Aug 18. PMID:19695264 doi:10.1016/j.jmb.2009.08.028
  2. Krajewski WW, Jones TA, Mowbray SL. Structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights. Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10499-504. Epub 2005 Jul 18. PMID:16027359

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