1kzy: Difference between revisions

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{{Seed}}
[[Image:1kzy.png|left|200px]]
[[Image:1kzy.png|left|200px]]


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{{STRUCTURE_1kzy|  PDB=1kzy  |  SCENE=  }}  
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===Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53===
===Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53===


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{{ABSTRACT_PUBMED_11877378}}
{{ABSTRACT_PUBMED_11877378}}


==Disease==
==About this Structure==
Known disease associated with this structure: Adrenal cortical carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Choroid plexus papilloma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Colorectal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Hepatocellular carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni-like syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Nasopharyngeal carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Pancreatic cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]]
[[1kzy]] is a 4 chain structure of [[P53]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZY OCA].  


==About this Structure==
==See Also==
1KZY is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZY OCA].
*[[P53|P53]]


==Reference==
==Reference==
<ref group="xtra">PMID:11877378</ref><references group="xtra"/>
<ref group="xtra">PMID:011877378</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cantor, S B.]]
[[Category: Cantor, S B.]]
Line 34: Line 22:
[[Category: Livingston, D M.]]
[[Category: Livingston, D M.]]
[[Category: Pavletich, N P.]]
[[Category: Pavletich, N P.]]
[[Category: Dna binding protein]]
[[Category: Parallel beta sheet]]
[[Category: Parallel beta sheet]]
[[Category: Protein binding]]
[[Category: Tandem-brct and linker complexed with non-brct protein]]
[[Category: Tandem-brct and linker complexed with non-brct protein]]
[[Category: Three-helix bundle]]
[[Category: Three-helix bundle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:41:25 2009''

Revision as of 14:32, 26 July 2012

File:1kzy.png

Template:STRUCTURE 1kzy

Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53

Template:ABSTRACT PUBMED 11877378

About this Structure

1kzy is a 4 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev. 2002 Mar 1;16(5):583-93. PMID:11877378 doi:https://dx.doi.org/10.1101/gad.959202

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