3et7: Difference between revisions
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[[Image:3et7.png|left|200px]] | |||
[[Image:3et7. | |||
{{STRUCTURE_3et7| PDB=3et7 | SCENE= }} | {{STRUCTURE_3et7| PDB=3et7 | SCENE= }} | ||
===Crystal structure of PYK2 complexed with PF-2318841=== | ===Crystal structure of PYK2 complexed with PF-2318841=== | ||
{{ABSTRACT_PUBMED_18951788}} | {{ABSTRACT_PUBMED_18951788}} | ||
==About this Structure== | ==About this Structure== | ||
[[3et7]] is a 1 chain structure of [[Focal adhesion kinase]] and [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ET7 OCA]. | |||
==See Also== | |||
*[[Focal adhesion kinase|Focal adhesion kinase]] | |||
*[[Tyrosine kinase|Tyrosine kinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018951788</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
[[Category: Han, S.]] | [[Category: Han, S.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
Revision as of 14:47, 26 July 2012
Crystal structure of PYK2 complexed with PF-2318841
Template:ABSTRACT PUBMED 18951788
About this Structure
3et7 is a 1 chain structure of Focal adhesion kinase and Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Walker DP, Bi FC, Kalgutkar AS, Bauman JN, Zhao SX, Soglia JR, Aspnes GE, Kung DW, Klug-McLeod J, Zawistoski MP, McGlynn MA, Oliver R, Dunn M, Li JC, Richter DT, Cooper BA, Kath JC, Hulford CA, Autry CL, Luzzio MJ, Ung EJ, Roberts WG, Bonnette PC, Buckbinder L, Mistry A, Griffor MC, Han S, Guzman-Perez A. Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6071-7. Epub 2008 Oct 11. PMID:18951788 doi:10.1016/j.bmcl.2008.10.030
