3k97: Difference between revisions

Revision as of 14:57, 26 July 2012

3k97 is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Kung PP, Huang B, Zhang G, Zhou JZ, Wang J, Digits JA, Skaptason J, Yamazaki S, Neul D, Zientek M, Elleraas J, Mehta P, Yin MJ, Hickey MJ, Gajiwala KS, Rodgers C, Davies JF, Gehring MR. Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone. J Med Chem. 2010 Jan 14;53(1):499-503. PMID:19908836 doi:10.1021/jm901209q

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 [[Image:3k97.png|left|200px]]
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 ===HSP90 N-terminal domain in complex with 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol===
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 ==See Also==
-*[[Heat Shock Proteins]]
+*[[Heat Shock Proteins|Heat Shock Proteins]]
 ==Reference==
-<ref group="xtra">PMID:19908836</ref><references group="xtra"/>
+<ref group="xtra">PMID:019908836</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Gajiwala, K S.]]
-[[Category: Acetylation]]
-[[Category: Alternative splicing]]
 [[Category: Atp binding domain]]
 [[Category: Atp-binding]]
 [[Category: Chaperone]]
-[[Category: Cytoplasm]]
 [[Category: Hsp90]]
 [[Category: Inhibition]]