2zxf: Difference between revisions

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{{Seed}}
[[Image:2zxf.png|left|200px]]
[[Image:2zxf.png|left|200px]]


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{{STRUCTURE_2zxf|  PDB=2zxf  |  SCENE=  }}  
{{STRUCTURE_2zxf|  PDB=2zxf  |  SCENE=  }}  


===Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with AP4A)===
===Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with AP4A)===


{{ABSTRACT_PUBMED_019710017}}


==Disease==
==About this Structure==
Known disease associated with this structure: Charcot-Marie-Tooth disease, type 2D OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600287 600287]], Neuropathy, distal hereditary motor, type V OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600287 600287]]
[[2zxf]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXF OCA].
 
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]


==About this Structure==
==Reference==
2ZXF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXF OCA].
<ref group="xtra">PMID:019710017</ref><references group="xtra"/>
[[Category: Glycine--tRNA ligase]]
[[Category: Glycine--tRNA ligase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aminoacyl-trna synthetase]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Ap4a]]
[[Category: Ap4a]]
[[Category: Atp]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Charcot-marie-tooth disease]]
[[Category: Charcot-marie-tooth disease]]
Line 36: Line 32:
[[Category: Protein biosynthesis]]
[[Category: Protein biosynthesis]]
[[Category: Trna]]
[[Category: Trna]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 16:43:36 2009''

Revision as of 15:19, 26 July 2012

File:2zxf.png

Template:STRUCTURE 2zxf

Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with AP4A)

Template:ABSTRACT PUBMED 019710017

About this Structure

2zxf is a 1 chain structure of Aminoacyl tRNA Synthetase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Guo RT, Chong YE, Guo M, Yang XL. Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis. J Biol Chem. 2009 Oct 16;284(42):28968-76. Epub 2009 Aug 26. PMID:19710017 doi:10.1074/jbc.M109.030692

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