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{{Seed}}
[[Image:2isp.png|left|200px]]
[[Image:2isp.png|left|200px]]


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{{STRUCTURE_2isp|  PDB=2isp  |  SCENE=  }}  
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===Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate===
===Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate===


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{{ABSTRACT_PUBMED_17209556}}
{{ABSTRACT_PUBMED_17209556}}


==About this Structure==
==About this Structure==
2ISP is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ISP OCA].  
[[2isp]] is a 4 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ISP OCA].  
 
==See Also==
*[[DNA polymerase|DNA polymerase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17209556</ref><references group="xtra"/>
<ref group="xtra">PMID:017209556</ref><references group="xtra"/>
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Leaving-group]]
[[Category: Leaving-group]]
[[Category: Nucleotidyl transferase]]
[[Category: Nucleotidyl transferase]]
 
[[Category: Transferase-dna complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:20:35 2009''

Revision as of 15:25, 26 July 2012

File:2isp.png

Template:STRUCTURE 2isp

Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate

Template:ABSTRACT PUBMED 17209556

About this Structure

2isp is a 4 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martinek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florian J, Warshel A, Goodman MF. Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Biochemistry. 2007 Jan 16;46(2):461-71. PMID:17209556 doi:10.1021/bi061517b

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