3ro4: Difference between revisions

Revision as of 15:34, 26 July 2012

3ro4 is a 2 chain structure of Ketohexokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Zhang X, Song F, Kuo GH, Xiang A, Gibbs AC, Abad MC, Sun W, Kuo LC, Sui Z. Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4762-7. Epub 2011 Jun 29. PMID:21767952 doi:10.1016/j.bmcl.2011.06.067

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 [[Image:3ro4.png|left|200px]]
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 ===X-ray Structure of Ketohexokinase in complex with an indazole compound derivative===
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