3in4: Difference between revisions
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[[Image:3in4.png|left|200px]] | [[Image:3in4.png|left|200px]] | ||
{{STRUCTURE_3in4| PDB=3in4 | SCENE= }} | {{STRUCTURE_3in4| PDB=3in4 | SCENE= }} | ||
===Bace1 with Compound 38=== | ===Bace1 with Compound 38=== | ||
{{ABSTRACT_PUBMED_20045648}} | {{ABSTRACT_PUBMED_20045648}} | ||
==About this Structure== | ==About this Structure== | ||
[[3in4]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IN4 OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020045648</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Olland, A M.]] | [[Category: Olland, A M.]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace-1]] | [[Category: Bace-1]] | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 17:12, 26 July 2012
Bace1 with Compound 38
Template:ABSTRACT PUBMED 20045648
About this Structure
3in4 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Malamas MS, Barnes K, Johnson M, Hui Y, Zhou P, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Pangalos M, Reinhart P, Robichaud AJ. Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem. 2010 Jan 15;18(2):630-9. Epub 2009 Dec 6. PMID:20045648 doi:10.1016/j.bmc.2009.12.007
