3le9: Difference between revisions

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{{Seed}}
[[Image:3le9.png|left|200px]]
[[Image:3le9.jpg|left|200px]]


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{{STRUCTURE_3le9|  PDB=3le9  |  SCENE=  }}  
{{STRUCTURE_3le9|  PDB=3le9  |  SCENE=  }}  


===Crystal structure of the catalytic domain of TACE with Indazolinone-phenyl-hydantoin inhibitor===
===Crystal structure of the catalytic domain of TACE with Indazolinone-phenyl-hydantoin inhibitor===


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{{ABSTRACT_PUBMED_20663669}}
{{ABSTRACT_PUBMED_20663669}}


==About this Structure==
==About this Structure==
3LE9 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LE9 OCA].  
[[3le9]] is a 2 chain structure of [[A Disintegrin And Metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LE9 OCA].  
 
==See Also==
*[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20663669</ref><references group="xtra"/>
<ref group="xtra">PMID:020663669</ref><references group="xtra"/>
[[Category: ADAM 17 endopeptidase]]
[[Category: ADAM 17 endopeptidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  8 11:48:56 2010''

Revision as of 18:05, 26 July 2012

File:3le9.png

Template:STRUCTURE 3le9

Crystal structure of the catalytic domain of TACE with Indazolinone-phenyl-hydantoin inhibitor

Template:ABSTRACT PUBMED 20663669

About this Structure

3le9 is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yu W, Tong L, Kim SH, Wong MK, Chen L, Yang DY, Shankar BB, Lavey BJ, Zhou G, Kosinski A, Rizvi R, Li D, Feltz RJ, Piwinski JJ, Rosner KE, Shih NY, Siddiqui MA, Guo Z, Orth P, Shah H, Sun J, Umland S, Lundell DJ, Niu X, Kozlowski JA. Biaryl substituted hydantoin compounds as TACE inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5286-9. Epub 2010 Jul 1. PMID:20663669 doi:10.1016/j.bmcl.2010.06.134

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