2wo8: Difference between revisions

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[[Image:2wo8.png|left|200px]]
[[Image:2wo8.png|left|200px]]


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{{STRUCTURE_2wo8|  PDB=2wo8  |  SCENE=  }}  
{{STRUCTURE_2wo8|  PDB=2wo8  |  SCENE=  }}  


===MMP12 COMPLEX WITH A BETA HYDROXY CARBOXYLIC ACID===
===MMP12 COMPLEX WITH A BETA HYDROXY CARBOXYLIC ACID===


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{{ABSTRACT_PUBMED_19703773}}
{{ABSTRACT_PUBMED_19703773}}


==About this Structure==
==About this Structure==
[[2wo8]] is a 4 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WO8 OCA].  
[[2wo8]] is a 4 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WO8 OCA].  


==See Also==
==See Also==
*[[Elastase]]
*[[Elastase|Elastase]]
*[[Matrix metalloproteinase|Matrix metalloproteinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19703773</ref><references group="xtra"/>
<ref group="xtra">PMID:019703773</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Macrophage elastase]]
[[Category: Macrophage elastase]]
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[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Metalloprotease]]
[[Category: Metalloprotease]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 18:19, 26 July 2012

File:2wo8.png

Template:STRUCTURE 2wo8

MMP12 COMPLEX WITH A BETA HYDROXY CARBOXYLIC ACID

Template:ABSTRACT PUBMED 19703773

About this Structure

2wo8 is a 4 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Holmes IP, Gaines S, Watson SP, Lorthioir O, Walker A, Baddeley SJ, Herbert S, Egan D, Convery MA, Singh OM, Gross JW, Strelow JM, Smith RH, Amour AJ, Brown D, Martin SL. The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. Epub 2009 Aug 6. PMID:19703773 doi:10.1016/j.bmcl.2009.07.155

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