3lpk: Difference between revisions
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[[Image:3lpk.png|left|200px]] | [[Image:3lpk.png|left|200px]] | ||
{{STRUCTURE_3lpk| PDB=3lpk | SCENE= }} | {{STRUCTURE_3lpk| PDB=3lpk | SCENE= }} | ||
===Structure of BACE Bound to SCH747123=== | ===Structure of BACE Bound to SCH747123=== | ||
{{ABSTRACT_PUBMED_20347593}} | {{ABSTRACT_PUBMED_20347593}} | ||
==About this Structure== | ==About this Structure== | ||
[[3lpk]] is a 2 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPK OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020347593</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 18:27, 26 July 2012
Structure of BACE Bound to SCH747123
Template:ABSTRACT PUBMED 20347593
About this Structure
3lpk is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cumming J, Babu S, Huang Y, Carrol C, Chen X, Favreau L, Greenlee W, Guo T, Kennedy M, Kuvelkar R, Le T, Li G, McHugh N, Orth P, Ozgur L, Parker E, Saionz K, Stamford A, Strickland C, Tadesse D, Voigt J, Zhang L, Zhang Q. Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg Med Chem Lett. 2010 May 1;20(9):2837-42. Epub 2010 Mar 12. PMID:20347593 doi:10.1016/j.bmcl.2010.03.050
