3heg: Difference between revisions

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[[Image:3heg.png|left|200px]]
[[Image:3heg.png|left|200px]]


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{{STRUCTURE_3heg|  PDB=3heg  |  SCENE=  }}  
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===P38 in complex with Sorafenib===
===P38 in complex with Sorafenib===


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{{ABSTRACT_PUBMED_20337484}}
{{ABSTRACT_PUBMED_20337484}}


==About this Structure==
==About this Structure==
[[3heg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HEG OCA].  
[[3heg]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HEG OCA].  


==See Also==
==See Also==
*[[Sorafenib]]
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
*[[Sorafenib|Sorafenib]]


==Reference==
==Reference==
<ref group="xtra">PMID:20337484</ref><references group="xtra"/>
<ref group="xtra">PMID:020337484</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]

Revision as of 18:31, 26 July 2012

File:3heg.png

Template:STRUCTURE 3heg

P38 in complex with Sorafenib

Template:ABSTRACT PUBMED 20337484

About this Structure

3heg is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry. 2010 May 4;49(17):3611-8. PMID:20337484 doi:10.1021/bi100070r

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