3dol: Difference between revisions

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Revision as of 19:05, 26 July 2012

File:3dol.png

Template:STRUCTURE 3dol

Crystal structure of L100I mutant HIV-1 reverse transcriptase in complex with GW695634.

Template:ABSTRACT PUBMED 18665583

About this Structure

3dol is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ren J, Chamberlain PP, Stamp A, Short SA, Weaver KL, Romines KR, Hazen R, Freeman A, Ferris RG, Andrews CW, Boone L, Chan JH, Stammers DK. Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J Med Chem. 2008 Aug 28;51(16):5000-8. Epub 2008 Jul 30. PMID:18665583 doi:10.1021/jm8004493

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