1tsr: Difference between revisions

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Revision as of 19:06, 26 July 2012

File:1tsr.png

Template:STRUCTURE 1tsr

P53 CORE DOMAIN IN COMPLEX WITH DNA

Template:ABSTRACT PUBMED 8023157

About this Structure

1tsr is a 5 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cho Y, Gorina S, Jeffrey PD, Pavletich NP. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science. 1994 Jul 15;265(5170):346-55. PMID:8023157
  2. Shortle D. Composites of local structure propensities: evidence for local encoding of long-range structure. Protein Sci. 2002 Jan;11(1):18-26. PMID:11742118
  3. Martin AC, Facchiano AM, Cuff AL, Hernandez-Boussard T, Olivier M, Hainaut P, Thornton JM. Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein. Hum Mutat. 2002 Feb;19(2):149-64. PMID:11793474 doi:10.1002/humu.10032
  4. Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630

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