4ajj: Difference between revisions

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[[Image:4ajj.png|left|200px]]
[[Image:4ajj.png|left|200px]]


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{{STRUCTURE_4ajj|  PDB=4ajj  |  SCENE=  }}  
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===rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid and N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido-propanamide===
===rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid and N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido-propanamide===


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{{ABSTRACT_PUBMED_22417091}}
{{ABSTRACT_PUBMED_22417091}}


==About this Structure==
==About this Structure==
[[4ajj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJJ OCA].  
[[4ajj]] is a 4 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJJ OCA].  
 
==See Also==
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]


==Reference==
==Reference==

Revision as of 19:17, 26 July 2012

File:4ajj.png

Template:STRUCTURE 4ajj

rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid and N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido-propanamide

Template:ABSTRACT PUBMED 22417091

About this Structure

4ajj is a 4 chain structure of Lactate Dehydrogenase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ward RA, Brassington C, Breeze AL, Caputo A, Critchlow S, Davies G, Goodwin L, Hassall G, Greenwood R, Holdgate GA, Mrosek M, Norman RA, Pearson S, Tart J, Tucker JA, Vogtherr M, Whittaker D, Wingfield J, Winter J, Hudson K. Design and synthesis of novel lactate dehydrogenase a inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306. Epub 2012 Mar 26. PMID:22417091 doi:10.1021/jm201734r

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