1e26: Difference between revisions

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{{Seed}}
[[Image:1e26.png|left|200px]]
[[Image:1e26.png|left|200px]]


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{{STRUCTURE_1e26|  PDB=1e26  |  SCENE=  }}  
{{STRUCTURE_1e26|  PDB=1e26  |  SCENE=  }}  


===DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.===
===DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.===


{{ABSTRACT_PUBMED_10194348}}


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==About this Structure==
The line below this paragraph, {{ABSTRACT_PUBMED_11052789}}, adds the Publication Abstract to the page
[[1e26]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
(as it appears on PubMed at http://www.pubmed.gov), where 11052789 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11052789}}


==About this Structure==
==See Also==
1E26 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
*[[Dihydrofolate reductase|Dihydrofolate reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:11052789</ref><references group="xtra"/>
<ref group="xtra">PMID:010194348</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Pneumocystis carinii]]
[[Category: Pneumocystis carinii]]
Line 34: Line 25:
[[Category: Yu, J.]]
[[Category: Yu, J.]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Oxidoreductase]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:08:56 2009''

Revision as of 19:23, 26 July 2012

File:1e26.png

Template:STRUCTURE 1e26

DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.

Template:ABSTRACT PUBMED 10194348

About this Structure

1e26 is a 1 chain structure of Dihydrofolate reductase with sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Biochemistry. 1999 Apr 6;38(14):4303-12. PMID:10194348 doi:10.1021/bi982728m

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