3cs7: Difference between revisions
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[[Image:3cs7.png|left|200px]] | [[Image:3cs7.png|left|200px]] | ||
{{STRUCTURE_3cs7| PDB=3cs7 | SCENE= }} | {{STRUCTURE_3cs7| PDB=3cs7 | SCENE= }} | ||
===FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one=== | ===FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one=== | ||
{{ABSTRACT_PUBMED_18550370}} | {{ABSTRACT_PUBMED_18550370}} | ||
==About this Structure== | ==About this Structure== | ||
[[3cs7]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CS7 OCA]. | |||
==See Also== | |||
*[[Factor Xa|Factor Xa]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018550370</ref><references group="xtra"/> | ||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Blood coagulation factor]] | [[Category: Blood coagulation factor]] | ||
[[Category: Calcium-binding]] | [[Category: Calcium-binding]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
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[[Category: Hydroxylation]] | [[Category: Hydroxylation]] | ||
[[Category: Plasma]] | [[Category: Plasma]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protein inhibitor complex]] | [[Category: Protein inhibitor complex]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 19:58, 26 July 2012
FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one
Template:ABSTRACT PUBMED 18550370
About this Structure
3cs7 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Qiao JX, Cheney DL, Alexander RS, Smallwood AM, King SR, He K, Rendina AR, Luettgen JM, Knabb RM, Wexler RR, Lam PY. Achieving structural diversity using the perpendicular conformation of alpha-substituted phenylcyclopropanes to mimic the bioactive conformation of ortho-substituted biphenyl P4 moieties: discovery of novel, highly potent inhibitors of Factor Xa. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4118-23. Epub 2008 May 29. PMID:18550370 doi:10.1016/j.bmcl.2008.05.095
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Alexander, R S.
- Blood coagulation
- Blood coagulation factor
- Calcium-binding
- Cleavage on pair of basic residue
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Plasma
- Protease
- Protein inhibitor complex
- Serine protease
- Zymogen
