1rff: Difference between revisions

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{{Seed}}
[[Image:1rff.png|left|200px]]
[[Image:1rff.png|left|200px]]


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===Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octapeptide KLNYYDPR, and tetranucleotide AGTT.===
===Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octapeptide KLNYYDPR, and tetranucleotide AGTT.===


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{{ABSTRACT_PUBMED_14761185}}


==Disease==
==About this Structure==
Known disease associated with this structure: Spinocerebellar ataxia, autosomal recessive with axonal neuropathy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607198 607198]]
[[1rff]] is a 6 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RFF OCA].


==About this Structure==
==See Also==
1RFF is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RFF OCA].
*[[Phosphodiesterase|Phosphodiesterase]]


==Reference==
==Reference==
<ref group="xtra">PMID:14761185</ref><references group="xtra"/>
<ref group="xtra">PMID:014761185</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Champoux, J J.]]
[[Category: Champoux, J J.]]
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[[Category: Hol, W G.]]
[[Category: Hol, W G.]]
[[Category: Interthal, H.]]
[[Category: Interthal, H.]]
[[Category: Hydrolase-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Transition state mimic]]
[[Category: Transition state mimic]]
[[Category: Vanadate complex]]
[[Category: Vanadate complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:21:28 2009''

Revision as of 21:13, 26 July 2012

File:1rff.png

Template:STRUCTURE 1rff

Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octapeptide KLNYYDPR, and tetranucleotide AGTT.

Template:ABSTRACT PUBMED 14761185

About this Structure

1rff is a 6 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Davies DR, Interthal H, Champoux JJ, Hol WG. Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. J Med Chem. 2004 Feb 12;47(4):829-37. PMID:14761185 doi:10.1021/jm030487x

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