3da6: Difference between revisions

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{{Seed}}
[[Image:3da6.png|left|200px]]
[[Image:3da6.jpg|left|200px]]


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{{STRUCTURE_3da6|  PDB=3da6  |  SCENE=  }}  
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===Crystal Structure of human JNK3 complexed with N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine===
===Crystal Structure of human JNK3 complexed with N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine===


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{{ABSTRACT_PUBMED_19062275}}
{{ABSTRACT_PUBMED_19062275}}


==About this Structure==
==About this Structure==
3DA6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA6 OCA].  
[[3da6]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA6 OCA].  
 
==See Also==
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]


==Reference==
==Reference==
Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase., Cee VJ, Cheng AC, Romero K, Bellon S, Mohr C, Whittington DA, Bak A, Bready J, Caenepeel S, Coxon A, Deak HL, Fretland J, Gu Y, Hodous BL, Huang X, Kim JL, Lin J, Long AM, Nguyen H, Olivieri PR, Patel VF, Wang L, Zhou Y, Hughes P, Geuns-Meyer S, Bioorg Med Chem Lett. 2008 Nov 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19062275 19062275]
<ref group="xtra">PMID:019062275</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: Wang, L.]]
[[Category: Wang, L.]]
[[Category: Whittington, D A.]]
[[Category: Whittington, D A.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Chromosomal rearrangement]]
[[Category: Cytoplasm]]
[[Category: Epilepsy]]
[[Category: Epilepsy]]
[[Category: Jnk3]]
[[Category: Jnk3]]
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[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan  7 09:45:11 2009''

Revision as of 21:15, 26 July 2012

File:3da6.png

Template:STRUCTURE 3da6

Crystal Structure of human JNK3 complexed with N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine

Template:ABSTRACT PUBMED 19062275

About this Structure

3da6 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cee VJ, Cheng AC, Romero K, Bellon S, Mohr C, Whittington DA, Bak A, Bready J, Caenepeel S, Coxon A, Deak HL, Fretland J, Gu Y, Hodous BL, Huang X, Kim JL, Lin J, Long AM, Nguyen H, Olivieri PR, Patel VF, Wang L, Zhou Y, Hughes P, Geuns-Meyer S. Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):424-7. Epub 2008 Nov 20. PMID:19062275 doi:10.1016/j.bmcl.2008.11.056

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