3dga: Difference between revisions

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{{Seed}}
[[Image:3dga.png|left|200px]]
[[Image:3dga.jpg|left|200px]]


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===Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF01302, NADPH, and dUMP===
===Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF01302, NADPH, and dUMP===


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{{ABSTRACT_PUBMED_19146480}}


==About this Structure==
==About this Structure==
3DGA is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGA OCA].  
[[3dga]] is a 4 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGA OCA].  
 
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Thymidylate synthase|Thymidylate synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19146480</ref><references group="xtra"/>
<ref group="xtra">PMID:019146480</ref><references group="xtra"/>
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Anderson, K S.]]
[[Category: Anderson, K S.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:48:37 2009''

Revision as of 21:51, 26 July 2012

File:3dga.png

Template:STRUCTURE 3dga

Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF01302, NADPH, and dUMP

Template:ABSTRACT PUBMED 19146480

About this Structure

3dga is a 4 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

See Also

Reference

  1. Dasgupta T, Chitnumsub P, Kamchonwongpaisan S, Maneeruttanarungroj C, Nichols SE, Lyons TM, Tirado-Rives J, Jorgensen WL, Yuthavong Y, Anderson KS. Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria. ACS Chem Biol. 2009 Jan 16;4(1):29-40. PMID:19146480 doi:10.1021/cb8002804

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