3cpb: Difference between revisions

Revision as of 22:02, 26 July 2012

3cpb is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Hu E, Tasker A, White RD, Kunz RK, Human J, Chen N, Burli R, Hungate R, Novak P, Itano A, Zhang X, Yu V, Nguyen Y, Tudor Y, Plant M, Flynn S, Xu Y, Meagher KL, Whittington DA, Ng GY. Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. J Med Chem. 2008 Jun 12;51(11):3065-8. Epub 2008 May 1. PMID:18447379 doi:https://dx.doi.org/10.1021/jm800188g

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 [[Image:3cpb.png|left|200px]]
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 ===Crystal structure of the VEGFR2 kinase domain in complex with a bisamide inhibitor===
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