1fcs: Difference between revisions
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New page: left|200px<br /><applet load="1fcs" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fcs, resolution 1.6Å" /> '''CRYSTAL STRUCTURE OF ... |
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[[Image:1fcs.gif|left|200px]]<br /><applet load="1fcs" size=" | [[Image:1fcs.gif|left|200px]]<br /><applet load="1fcs" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1fcs, resolution 1.6Å" /> | caption="1fcs, resolution 1.6Å" /> | ||
'''CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION'''<br /> | '''CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION'''<br /> | ||
==Overview== | ==Overview== | ||
The three-dimensional structure of sperm whale myoglobin | The three-dimensional structure of sperm whale myoglobin His64(E7)-->Val,Thr67(E10)-->Arg double mutant has been studied by X-ray crystallography at 1.6 A resolution, and refined to a crystallographic R-factor of 0.197. The Arg67(E10) side chain is extended in the direction of the ligand binding site, and its NH1 atom is at a distance of 3.11 A from the NH1 atom of Arg45(CD3), which is also pointing towards the distal site. Both are kept in this position by hydrogen bonding and electrostatic interactions with a solvent sulfate ion, located amongst the two, on the protein surface. No liganded water molecule is present at the sixth coordination position of the Fe(III) heme. | ||
==About this Structure== | ==About this Structure== | ||
1FCS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon] with SO4 and HEM as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | 1FCS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FCS OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Physeter catodon]] | [[Category: Physeter catodon]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Allocatelli, C | [[Category: Allocatelli, C Travaglini.]] | ||
[[Category: Bolognesi, M.]] | [[Category: Bolognesi, M.]] | ||
[[Category: Brancaccio, A.]] | [[Category: Brancaccio, A.]] | ||
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[[Category: oxygen transport]] | [[Category: oxygen transport]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:37:20 2008'' | ||
