3dhk: Difference between revisions

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[[Image:3dhk.png|left|200px]]
[[Image:3dhk.png|left|200px]]


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{{STRUCTURE_3dhk|  PDB=3dhk  |  SCENE=  }}  
{{STRUCTURE_3dhk|  PDB=3dhk  |  SCENE=  }}  


===Bisphenylic Thrombin Inhibitors===
===Bisphenylic Thrombin Inhibitors===


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{{ABSTRACT_PUBMED_19520086}}
{{ABSTRACT_PUBMED_19520086}}


==About this Structure==
==About this Structure==
[[3dhk]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHK OCA].  
[[3dhk]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHK OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19520086</ref><references group="xtra"/>
<ref group="xtra">PMID:019520086</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood clotting-hydrolase inhibitor complex]]
[[Category: Blood clotting/hydrolase inhibitor]]
[[Category: Blood clotting/hydrolase inhibitor]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 22:48, 26 July 2012

File:3dhk.png

Template:STRUCTURE 3dhk

Bisphenylic Thrombin Inhibitors

Template:ABSTRACT PUBMED 19520086

About this Structure

3dhk is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Baum B, Muley L, Heine A, Smolinski M, Hangauer D, Klebe G. Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin. J Mol Biol. 2009 Aug 21;391(3):552-64. Epub 2009 Jun 9. PMID:19520086 doi:10.1016/j.jmb.2009.06.016

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