3lqa: Difference between revisions

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{{Seed}}
[[Image:3lqa.png|left|200px]]
[[Image:3lqa.png|left|200px]]


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===Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab===
===Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab===


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{{ABSTRACT_PUBMED_20357769}}


==Disease==
==About this Structure==
Known disease associated with this structure: CD4  lymphocyte deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=186940 186940]], Lupus erythematosus, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=186940 186940]]
[[3lqa]] is a 4 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQA OCA].


==About this Structure==
==See Also==
3LQA is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQA OCA].
*[[Antibody|Antibody]]


==Reference==
==Reference==
<ref group="xtra">PMID:20357769</ref><references group="xtra"/>
<ref group="xtra">PMID:020357769</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Poly reactivity]]
[[Category: Poly reactivity]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:40:39 2010''

Revision as of 23:15, 26 July 2012

File:3lqa.png

Template:STRUCTURE 3lqa

Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab

Template:ABSTRACT PUBMED 20357769

About this Structure

3lqa is a 4 chain structure of Antibody with sequence from Homo sapiens and Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Diskin R, Marcovecchio PM, Bjorkman PJ. Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. Nat Struct Mol Biol. 2010 May;17(5):608-13. Epub 2010 Mar 31. PMID:20357769 doi:10.1038/nsmb.1796

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