2va7: Difference between revisions

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{{Seed}}
[[Image:2va7.png|left|200px]]
[[Image:2va7.png|left|200px]]


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{{STRUCTURE_2va7|  PDB=2va7  |  SCENE=  }}  
{{STRUCTURE_2va7|  PDB=2va7  |  SCENE=  }}  


===X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 27===
===X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 27===


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{{ABSTRACT_PUBMED_17985862}}
{{ABSTRACT_PUBMED_17985862}}


==About this Structure==
==About this Structure==
2VA7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA7 OCA].  
[[2va7]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA7 OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17985862</ref><references group="xtra"/>
<ref group="xtra">PMID:017985862</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Mauger, R C.]]
[[Category: Mauger, R C.]]
[[Category: Murray, C W.]]
[[Category: Murray, C W.]]
[[Category: Olsson, L.]]
[[Category: Olsson, L L.]]
[[Category: Patel, S.]]
[[Category: Patel, S.]]
[[Category: Spear, N.]]
[[Category: Spear, N.]]
[[Category: Sylvester, M.]]
[[Category: Sylvester, M.]]
[[Category: Tian, G.]]
[[Category: Tian, G.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:49:01 2009''

Revision as of 23:23, 26 July 2012

File:2va7.png

Template:STRUCTURE 2va7

X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 27

Template:ABSTRACT PUBMED 17985862

About this Structure

2va7 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Edwards PD, Albert JS, Sylvester M, Aharony D, Andisik D, Callaghan O, Campbell JB, Carr RA, Chessari G, Congreve M, Frederickson M, Folmer RH, Geschwindner S, Koether G, Kolmodin K, Krumrine J, Mauger RC, Murray CW, Olsson LL, Patel S, Spear N, Tian G. Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency. J Med Chem. 2007 Nov 29;50(24):5912-25. Epub 2007 Nov 7. PMID:17985862 doi:https://dx.doi.org/10.1021/jm070829p

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