3opm: Difference between revisions

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[[Image:3opm.png|left|200px]]
[[Image:3opm.png|left|200px]]


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{{STRUCTURE_3opm|  PDB=3opm  |  SCENE=  }}  
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===Crystal Structure of Human DPP4 Bound to TAK-294===
===Crystal Structure of Human DPP4 Bound to TAK-294===


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{{ABSTRACT_PUBMED_21764322}}
{{ABSTRACT_PUBMED_21764322}}


==About this Structure==
==About this Structure==
[[3opm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPM OCA].  
[[3opm]] is a 4 chain structure of [[Dipeptidyl peptidase]] and [[Farnesyl diphosphate synthase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPM OCA].  
 
==See Also==
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]


==Reference==
==Reference==

Revision as of 23:27, 26 July 2012

File:3opm.png

Template:STRUCTURE 3opm

Crystal Structure of Human DPP4 Bound to TAK-294

Template:ABSTRACT PUBMED 21764322

About this Structure

3opm is a 4 chain structure of Dipeptidyl peptidase and Farnesyl diphosphate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Banno Y, Miyamoto Y, Sasaki M, Oi S, Asakawa T, Kataoka O, Takeuchi K, Suzuki N, Ikedo K, Kosaka T, Tsubotani S, Tani A, Funami M, Tawada M, Yamamoto Y, Aertgeerts K, Yano J, Maezaki H. Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554. Bioorg Med Chem. 2011 Aug 15;19(16):4953-70. Epub 2011 Jun 28. PMID:21764322 doi:10.1016/j.bmc.2011.06.059

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