2qel: Difference between revisions

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[[Image:2qel.png|left|200px]]
[[Image:2qel.png|left|200px]]


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{{STRUCTURE_2qel|  PDB=2qel  |  SCENE=  }}  
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===Crystal structure of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S- heated protein===
===Crystal structure of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S- heated protein===


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{{ABSTRACT_PUBMED_17671371}}
{{ABSTRACT_PUBMED_17671371}}


==About this Structure==
==About this Structure==
[[2qel]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QEL OCA].  
[[2qel]] is a 4 chain structure of [[Transthyretin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QEL OCA].  
 
==See Also==
*[[Transthyretin|Transthyretin]]


==Reference==
==Reference==
<ref group="xtra">PMID:17671371</ref><ref group="xtra">PMID:11106758</ref><ref group="xtra">PMID:10986125</ref><references group="xtra"/>
<ref group="xtra">PMID:017671371</ref><ref group="xtra">PMID:011106758</ref><ref group="xtra">PMID:010986125</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Karlsson, A.]]
[[Category: Karlsson, A.]]

Revision as of 23:50, 26 July 2012

File:2qel.png

Template:STRUCTURE 2qel

Crystal structure of the highly amyloidogenic transthyretin mutant TTR G53S/E54D/L55S- heated protein

Template:ABSTRACT PUBMED 17671371

About this Structure

2qel is a 4 chain structure of Transthyretin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Karlsson A, Sauer-Eriksson AE. Heating of proteins as a means of improving crystallization: a successful case study on a highly amyloidogenic triple mutant of human transthyretin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt, 8):695-700. Epub 2007 Jul 21. PMID:17671371 doi:10.1107/S1744309107033957
  2. Eneqvist T, Andersson K, Olofsson A, Lundgren E, Sauer-Eriksson AE. The beta-slip: a novel concept in transthyretin amyloidosis. Mol Cell. 2000 Nov;6(5):1207-18. PMID:11106758
  3. Hornberg A, Eneqvist T, Olofsson A, Lundgren E, Sauer-Eriksson AE. A comparative analysis of 23 structures of the amyloidogenic protein transthyretin. J Mol Biol. 2000 Sep 22;302(3):649-69. PMID:10986125 doi:10.1006/jmbi.2000.4078

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