3frj: Difference between revisions
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[[Image:3frj.png|left|200px]] | [[Image:3frj.png|left|200px]] | ||
{{STRUCTURE_3frj| PDB=3frj | SCENE= }} | {{STRUCTURE_3frj| PDB=3frj | SCENE= }} | ||
===Crystal Structure of 11b-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Piperidyl Benzamide Inhibitor=== | ===Crystal Structure of 11b-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Piperidyl Benzamide Inhibitor=== | ||
{{ABSTRACT_PUBMED_19217779}} | {{ABSTRACT_PUBMED_19217779}} | ||
==About this Structure== | ==About this Structure== | ||
[[3frj]] is a 2 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRJ OCA]. | |||
==See Also== | |||
*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019217779</ref><references group="xtra"/> | ||
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
Revision as of 23:52, 26 July 2012
Crystal Structure of 11b-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Piperidyl Benzamide Inhibitor
Template:ABSTRACT PUBMED 19217779
About this Structure
3frj is a 2 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rew Y, McMinn DL, Wang Z, He X, Hungate RW, Jaen JC, Sudom A, Sun D, Tu H, Ursu S, Villemure E, Walker NP, Yan X, Ye Q, Powers JP. Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1797-801. Epub 2009 Jan 23. PMID:19217779 doi:10.1016/j.bmcl.2009.01.058