3m2w: Difference between revisions

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{{Seed}}
[[Image:3m2w.png|left|200px]]
[[Image:3m2w.jpg|left|200px]]


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{{STRUCTURE_3m2w|  PDB=3m2w  |  SCENE=  }}  
{{STRUCTURE_3m2w|  PDB=3m2w  |  SCENE=  }}  


===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor===
===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor===


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{{ABSTRACT_PUBMED_20591669}}
{{ABSTRACT_PUBMED_20591669}}


==About this Structure==
==About this Structure==
3M2W is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA].  
[[3m2w]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA].  
 
==See Also==
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20591669</ref><references group="xtra"/>
<ref group="xtra">PMID:020591669</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Spiroazetidine-tetracycle]]
[[Category: Spiroazetidine-tetracycle]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:37:21 2010''

Revision as of 00:20, 27 July 2012

File:3m2w.png

Template:STRUCTURE 3m2w

Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor

Template:ABSTRACT PUBMED 20591669

About this Structure

3m2w is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Revesz L, Schlapbach A, Aichholz R, Dawson J, Feifel R, Hawtin S, Littlewood-Evans A, Koch G, Kroemer M, Mobitz H, Scheufler C, Velcicky J, Huppertz C. In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4719-23. Epub 2010 Apr 11. PMID:20591669 doi:10.1016/j.bmcl.2010.04.023

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