2y80: Difference between revisions

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[[Image:2y80.jpg|left|200px]]
[[Image:2y80.png|left|200px]]


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{{STRUCTURE_2y80|  PDB=2y80  |  SCENE=  }}  
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===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH AMINOINDANE AND PHENYLPYRROLIDINE P4 MOTIFS===
===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH AMINOINDANE AND PHENYLPYRROLIDINE P4 MOTIFS===


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{{ABSTRACT_PUBMED_21349710}}


==About this Structure==
==About this Structure==
[[2y80]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y80 OCA].  
[[2y80]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y80 OCA].  
 
==See Also==
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
<ref group="xtra">PMID:21349710</ref><references group="xtra"/>
<ref group="xtra">PMID:021349710</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Young, R J.]]
[[Category: Young, R J.]]
[[Category: Zhou, P.]]
[[Category: Zhou, P.]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Hydrolase]]
[[Category: Serine protease]]

Revision as of 00:33, 27 July 2012

File:2y80.png

Template:STRUCTURE 2y80

STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH AMINOINDANE AND PHENYLPYRROLIDINE P4 MOTIFS

Template:ABSTRACT PUBMED 21349710

About this Structure

2y80 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Young RJ, Adams C, Blows M, Brown D, Burns-Kurtis CL, Chan C, Chaudry L, Convery MA, Davies DE, Exall AM, Foster G, Harling JD, Hortense E, Irvine S, Irving WR, Jackson S, Kleanthous S, Pateman AJ, Patikis AN, Roethka TJ, Senger S, Stelman GJ, Toomey JR, West RI, Whittaker C, Zhou P, Watson NS. Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1582-7. Epub 2011 Feb 1. PMID:21349710 doi:10.1016/j.bmcl.2011.01.131

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