2fhy: Difference between revisions

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[[Image:2fhy.png|left|200px]]
[[Image:2fhy.png|left|200px]]


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{{STRUCTURE_2fhy|  PDB=2fhy  |  SCENE=  }}  
{{STRUCTURE_2fhy|  PDB=2fhy  |  SCENE=  }}  


===Structure of human liver FPBase complexed with a novel benzoxazole as allosteric inhibitor===
===Structure of human liver FPBase complexed with a novel benzoxazole as allosteric inhibitor===


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{{ABSTRACT_PUBMED_16442285}}
{{ABSTRACT_PUBMED_16442285}}


==About this Structure==
==About this Structure==
[[2fhy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHY OCA].  
[[2fhy]] is a 4 chain structure of [[Fructose-1%2C6-bisphosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHY OCA].  
 
==See Also==
*[[Fructose-1%2C6-bisphosphatase|Fructose-1%2C6-bisphosphatase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16442285</ref><ref group="xtra">PMID:16446092</ref><references group="xtra"/>
<ref group="xtra">PMID:016442285</ref><ref group="xtra">PMID:016446092</ref><references group="xtra"/>
[[Category: Fructose-bisphosphatase]]
[[Category: Fructose-bisphosphatase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 01:40, 27 July 2012

File:2fhy.png

Template:STRUCTURE 2fhy

Structure of human liver FPBase complexed with a novel benzoxazole as allosteric inhibitor

Template:ABSTRACT PUBMED 16442285

About this Structure

2fhy is a 4 chain structure of Fructose-1,6-bisphosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. von Geldern TW, Lai C, Gum RJ, Daly M, Sun C, Fry EH, Abad-Zapatero C. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1811-5. Epub 2006 Jan 25. PMID:16442285 doi:10.1016/j.bmcl.2006.01.015
  2. Lai C, Gum RJ, Daly M, Fry EH, Hutchins C, Abad-Zapatero C, von Geldern TW. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1807-10. Epub 2006 Jan 30. PMID:16446092 doi:10.1016/j.bmcl.2006.01.014

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