2qd9: Difference between revisions

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Revision as of 01:42, 27 July 2012

File:2qd9.png

Template:STRUCTURE 2qd9

P38 Alpha Map Kinase inhibitor based on heterobicyclic scaffolds

Template:ABSTRACT PUBMED 17664068

About this Structure

2qd9 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Murali Dhar TG, Wrobleski ST, Lin S, Furch JA, Nirschl DS, Fan Y, Todderud G, Pitt S, Doweyko AM, Sack JS, Mathur A, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Synthesis and SAR of p38alpha MAP kinase inhibitors based on heterobicyclic scaffolds. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5019-24. Epub 2007 Jul 21. PMID:17664068 doi:10.1016/j.bmcl.2007.07.029

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