2r27: Difference between revisions

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{{Seed}}
[[Image:2r27.png|left|200px]]
[[Image:2r27.png|left|200px]]


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{{STRUCTURE_2r27|  PDB=2r27  |  SCENE=  }}  
{{STRUCTURE_2r27|  PDB=2r27  |  SCENE=  }}  


===Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S===
===Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S===


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{{ABSTRACT_PUBMED_17888947}}
{{ABSTRACT_PUBMED_17888947}}


==Disease==
==About this Structure==
Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147450 147450]]
[[2r27]] is a 2 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R27 OCA].


==About this Structure==
==See Also==
2R27 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R27 OCA].
*[[Superoxide Dismutase|Superoxide Dismutase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17888947</ref><references group="xtra"/>
<ref group="xtra">PMID:017888947</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Superoxide dismutase]]
[[Category: Superoxide dismutase]]
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[[Category: Roberts, B R.]]
[[Category: Roberts, B R.]]
[[Category: Tainer, J A.]]
[[Category: Tainer, J A.]]
[[Category: Acetylation]]
[[Category: Amyotrophic lateral sclerosis]]
[[Category: Amyotrophic lateral sclerosis]]
[[Category: Antioxidant]]
[[Category: Antioxidant]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Copper]]
[[Category: Cu ion]]
[[Category: Cu ion]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:33:31 2009''

Revision as of 01:53, 27 July 2012

File:2r27.png

Template:STRUCTURE 2r27

Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S

Template:ABSTRACT PUBMED 17888947

About this Structure

2r27 is a 2 chain structure of Superoxide Dismutase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Roberts BR, Tainer JA, Getzoff ED, Malencik DA, Anderson SR, Bomben VC, Meyers KR, Karplus PA, Beckman JS. Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J Mol Biol. 2007 Nov 2;373(4):877-90. Epub 2007 Aug 2. PMID:17888947 doi:https://dx.doi.org/10.1016/j.jmb.2007.07.043

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